Misoprostol (pge1) versus dinoprostone gel (pge2) in induction of labour in late intra uterine fetal death with unfavourable cervix: a prospective comparative study

Abstract

To compare the efficacy, safety and tolerance of misoprostol versus dinoprostone gel in induction of labour in the case of late Intra Uterine Fetal Death (IUFD) with unfavourable cervix.Materials and methods: This prospective study included a consecutive series of 40 women gravid up to fourth with IUFD after 28 weeks of gestation between March 2013 to Feb 2014. Women were divided into two groups. Each group consisted of 20 women. First group of women received 100μg of misoprostol per vaginally at four hourly intervals (maximum 600μg in 24 hours). Second group of women received dinoprostone gel 0.5 mg intracervically at every 6 hours, maximum 2 doses in 24 hours. Oxytocin was given for augmentation if needed