Reference range values of haematological parameters of healthy adults in western rajasthan

Abstract

Objectives: This study was done to establish the normal values of various haematological parameters for healthy adult of Western Rajasthan (males and females) and to compare these values with those obtained for other population in both India and tropical countries. Methods: This study was under taken in reference adult Western Rajasthan Population in the area of Jodhpur, India. A total 1000 healthy volunteers whose ages ranged between 20–50 years, were investigated. All laboratory analysis was conducted under standardized conditions atL.N. Memorial Hospital & Research Centre, Jodhpur.Results:In Males, the mean Haemoglobin concentration (Hb) of 14.03 g/dl and Haematocrit (HCT) ratio of 44% were significantly higherthan femalevalue of 12.50 g/dl and 40% respectively. The mean Red Blood Cell (RBC) countof 4.90 x 106/μL in males was also significantly higher than the corresponding value of 4.50 x 106/μL infemales (p<0.05). The value of Mean Corpuscular Volume (MCV) in males (88.12 fL) wassignificantly higher than in females (86.32 fL), (p<0.05). Similarly the Mean CorpuscularHaemoglobin (MCH) was significantly higher in males than corresponding values in females (p<0.05). Mean Corpuscular Haemoglobin Concentration (MCHC) was significantly higher in females than corresponding values in males (p<0.05). On the other hand,the mean White Blood Cell count (WBC) of 7.76x 103/μL in males was lower than mean value of7.95 x 103/μLin females (p<0.05). Similarly the values for Platelet count of 211 x 103/μL in males werealso significantly lower than corresponding values of 278 x 103/μL in females (p<0.05). Conclusions: This study has established baseline values for haematological parameters in healthy Western Rajasthanadults and surrounding areas. The sex difference of measured levels of all of theseparameters has attained statistical significance. When the observed values of this study werecompared with those quoted for the methods in use and those drawn from different populations,significant differences were revealed. Such differences are of accurate clinical interpretation ofhaematological investigation of patients.